Tag Archives: MRI

When someone is changing right in front of your eyes !!!!!

When you have a loved one and you start to notice different behaviors such as if they are usually easy going, kind hearted, gentle, would never hurt you mentally and or physically, then in a fast amount of time they become angry, mean, temper tantrums, violent mentally, You cant put your finger on it but you know something is wrong, They normally were right on top of everything bills, what ever needed to be done and instead even items on a grocery list are not there, bills not getting paid, loosing important papers, loosing medications just picked up at the pharmacy.

When asking what’s going on, You receive a very defensive person, they may kick you out of the house, or their bedroom, they become isolated, I feel this is out of depression and fear of what is happening to them. They know something is not right, they may sleep more, drink more, have more pain specially in the head, emotional episodes that were confusing . Behavior that makes them not appropriate in public, They fight you on everything,

Finally they may if a strong person may come to you and cry, like a baby, admitting they need help, they don’t know what is wrong, but they are forgetting things, not just normal age type things, like where they are, where they are going, after you give directions you still end up at the wrong place, they learn to adapt and how to cover up what’s happening. But still defensive, they can become paranoid, pace the floor, urinate in their pants and can’t hold it anymore, accuse you of things out of paranoia.

Their eating habits may change, they may eat more or less, or in this situation eat more, hide food, keep it in their car or locked in their room. You ask, they don’t have any, a full box of donuts gone no one else had any, almost like they don’t realize there doing it and deny it.

Even if they trust you enough to ask for help, its very important to their self esteem you don’t put them down and let them know you will always be there with them and won’t leave them. But then the next day they can transfer money out of the bank, take your keys, anything to remain in control over there life that they so eagerly want to hold on to.

If you feel well maybe it’s just me, or a phase, but other family members say things like, is so and so ok? Why? He is looking like he’s not here with us at the table, like vacant. Or I saw this person sitting on a stool starring off into space and wasn’t really there. Or finding them doing odd things like falling asleep sitting straight up like they were awake but asleep, or watering the pavement saying they are watering the grass.

It could be numerous things, Dementia, Alzheimer’s, a Traumatic brain injury, stroke, TIA’s, personality disorder, medications, so you must offer support the biggest fear they have is being alone, so you must reassure them you can be trusted and are their for them no matter what, other wise they won’t tell the truth of what’s going on. Brain Atrophy and alcohol and or past alcohol can escalade these symptoms, Smoking pot can also escalate these symptoms specially if used along length of time.

So If you notice anything of these symptoms, Please with out putting someone down, or making them feel bad, Be there, be strong for them even if you cry in another room.

If you notice these changes and happens in a quick amount of time like 6 months, you need to get them into a Neurologist, get a MRI, have cognitive thinking testing, and if it a reputable place they will ask the loved ones what they have noticed because they will not indulge the information to the Dr out of fear of a diagnosis. You have to be the person who steps up and recognizes there is something wrong, you can’t still your head in the sand. The sooner for a diagnosis, sooner for treatment and some Brain issues can be reversed or slowed down. So it’s not a time to take lightly.

If a accurate diagnosis is made its important how you and your loved ones can find out what you can do to help this person to keep them at their best, if they are tired, let them sleep, if they can’t get something done, oh well, learn to make small things just that! But also helping your loved one is the best gift you can give them.

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Is a MRI Toxic!!!!

[New post] Study raises questions about the safety of MRI contrast agent; authors call for FDA action
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Study raises questions about the safety of MRI contrast agent; authors call for FDA action
by Ralph Turchiano

Public Release: 6-Apr-2016

“patients with kidney disease were developing nephrogenic systemic fibrosis (NSF) due to the inability to clear gadolinium from their bodies”

MedInsight Research Institute

APRIL 6, 2016, Ariel, Israel – An article published today in the Springer journal BioMetals raises serious questions about the safety of the gadolinium-based contrast agents that are used in about 30 percent of magnetic resonance imaging (MRI) scans. In their literature review, researchers from MedInsight Research Institute and Israel’s Ariel University analyzed studies detailing the known and proposed mechanisms of retained gadolinium toxicity. According to lead author Moshe Rogosnitzky, “Although gadolinium is bound to chelating agents designed to flush out the rare metal following an MRI, it has been found to deposit in the brain, bone, and other organs.”

Rogosnitzky said that this finding contradicts the longstanding belief that patients with normal kidney function are not at risk for gadolinium accretion. In 2007, the U.S. Food and Drug Administration (FDA) ordered a black box warning for gadolinium-based contrast agents following the discovery that patients with kidney disease were developing nephrogenic systemic fibrosis (NSF) due to the inability to clear gadolinium from their bodies. In July 2015, the FDA announced it was evaluating the risk of brain-deposits in patients who undergo repeated exposure to gadolinium-based contrast agents. “At the time, FDA claimed that available information did not identify any adverse health effects. In the face of the information contained in our study, we believe this position is no longer tenable,” said Rogosnitzky.

Study author and toxicologist Dr. Stacy Branch underscored the urgent need for the FDA to take action. “Given the ever-growing toxicological and gadolinium tissue retention data, it is vital that the FDA promptly leads efforts, including retrospective and prospective clinical studies, to better define the connection between GBCA-exposure and adverse health events,” she said. “This is needed to guide the choice of preventive methods, achieve accurate diagnoses, implement effective treatment approaches, and spark research for the design of safer contrast agents and imaging protocols.”

Rogosnitzky, who heads the Center for Drug Repurposing at Ariel University, called upon the scientific community to quickly develop treatments for gadolinium overload. “Our literature review did not reveal a single suitable drug to swiftly remove gadolinium from the body,” he said. “In one study, the authors estimated it might take up to 156 years to remove a patient’s stored gadolinium using a particular drug.” Rogosnitzky believes that a good first step is to study existing chelator drugs used for other metal toxicities in order to assess their possible utility in gadolinium accumulation.

The published article sounds the alarm about the gap in scientific knowledge about treatment for gadolinium toxicity. “With the ominous discovery that gadolinium is retained in healthy patients, there is a critical shortage of scientific information regarding how to assess gadolinium toxicity, and perhaps most importantly, how to treat it,” Rogosnitzky said.

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The article, “Gadolinium-Based Contrast Agent Toxicity – A Review of Known and Proposed Mechanisms,” can be accessed at http://link.springer.com/article/10.1007/s10534-016-9931-7.
Ralph Turchiano | Apri

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